Nana is the archenemy of Alex the Lion of the Madagascar franchise. In the first movie, she is a minor antagonist and she is the secondary antagonist in the sequel. Despite being old, she is capable of beating up a lion.
In the second film, she is the leader of New Yorkers. Near the end, she is allowed to win and tricked by Alex and his father Zuba at once, by Alex giving her purse to Makunga, letting her out, and tricking him into beating him and taking him away.